On November 19, 2021, President Joe Biden temporarily transferred his powers and duties to Vice President Kamala Harris before undergoing a colonoscopy, making her acting president from 10:10 a.m. until 11:35 a.m. This was the first time a woman held the powers and duties of the president of the United States.
Biden had a benign but pre-cancerous polyp removed from his colon during that procedure.